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10 - 12 February 2017, MECC Maastricht,The Netherlands.

This Meeting has been awarded 15 CME credits.

Five year results with the Artiflex myopia phakic intraocular lens: long-term visual function, efficacy, safety and endothelial cell loss

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Session Details

Session Title: Refractive
Session Date/Time: Friday 10/02/2017 | 10:30-12:30
Paper Time: 12:00
Venue: Brussels Room 0.4

First Author: S. Jonker THE NETHERLANDS
Co Author(s): A. Ronden   T. Berendschot  I. Saelens  N. Bauer  R. Nuijts     

Abstract Details


Prospective evaluation of visual and refractive parameters, efficacy, safety and endothelial cell loss in a large group of patients five and ten years after implantation with the Artiflex phakic intraocular lens (pIOL) for myopia.


Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.


Data from all myopic patients implanted with the Artiflex pIOL (Ophtec, Groningen, the Netherlands) from 2003 until July 2016 were collected for prospective analysis. Mean preoperative age was 39.6ᄆ10.6. One-hundred-and-sixty-six patients (293 eyes) were implanted, and 133 patients (238 eyes) and 77 patients (146 eyes) completed a follow-up of 1 and 5 years, respectively. Both visual and refractive, topographic and intraocular parameters and endothelial cell density were measured preoperatively, 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year follow-up.


Mean logMAR UDVA was 0.004ᄆ0.131 and 0.046ᄆ0.158 logMAR respectively 1 and 5 years postoperatively (p < 0.001). Mean logMAR CDVA was -0.071ᄆ0.097 and -0.052ᄆ0.080 logMAR 1 and 5 years postoperatively (p < 0.001). Mean spherical equivalent (SE) was -0.16ᄆ0.46 D and -0.35ᄆ0.62 D respectively 1 and 5 years postoperatively (p = 0.003). After 1 and 5 years, 96% and 91% of eyes were within 1.0 D of the intended correction. Mean chronic EC loss from 6 months to 5 years postoperatively was -10.7% (p<0.001).


Over 5 years, both uncorrected and corrected visual acuity showed a minimal but statistically significant (p < 0.001) increase of 0.042 logMAR and 0.021 logMAR, respectively. A similar statistically significant (p = 0.003) but minimal myopisation of -0.18 D was witnessed over 5 years. There was a progressive increased annual endothelial cell loss of -2.38%, which was significantly higher than the expected physiological endothelial cell loss of -0.6% per year.

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