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Central toxic keratopathy after photorefractive surgery

Poster Details

First Author: H.Mohammad Rabei IRAN

Co Author(s):    A. Shojaei Baghini   K. Sheibani           

Abstract Details


To report a distinct clinical syndrome, central toxic keratopathy, as a cause of early postoperative corneal opacity.


Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


Twelve eyes from 6 patients who presented with decreased vision 3 to 9 days postoperatively accompanied by central corneal opacity, corneal melting and hyperopic shift are presented. They underwent PRK (3 patients), LASEK (1patient) and Epi-LASIK (2 patients); and mitomycin C (0.02% dilution) had been applied for all of them.


The opacification persisted for a minimum of two months to a maximum of 6 months before clearing. 1-2 line loss of BCVA persisted in two patients after 6 months.


In central toxic keratopathy despite the clearance of opacity in most of cases, an irreversible complication might remain in few patients. FINANCIAL INTEREST: NONE

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