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Outcomes of AcrySof Cachet phakic intraocular lens during a five year follow-up

Poster Details

First Author: J.Alio SPAIN

Co Author(s):    E. Sala   A. Plaza           

Abstract Details


To evaluate visual and aberrometric outcomes of the AcrySof Cachet (Alcon Laboratories Inc) angle-supported phakic intraocular lens (pIOL) for the correction of moderate to high myopia in patients after 5 years follow-up.


Vissum-Corporación Oftalmológica de Alicante. Alicante, Spain.


This retrospective, observational, consecutive, study included a total of 115 eyes of 75 patients with moderate to high myopia that had implantation of an AcrySoft Cachet pIOL with the aim of minimizing the refractive error. Age ranging between 21 to 60 years.The optical aberrations were measured with the Topcon KR-1W aberrometer. Coma and spherical aberrations, 3 rd- and 4 th-order aberrations, and total higher order aberrations (HOAs) were calculated for a 6 mm pupil diameter after 5 years of implantation. Endothelial cell images were collected in the central region of the cornea at 3,6 and 12 months, 2,3,4 and 5 years. Visual acuity outcomes were evaluated preoperatively and postoperatively during a 5 year follow-up.


Mean manifest spherical equivalent refraction reduced significantly from -11,78±3,33 diopters (D) to -0.63±0.88 D at 5 years. Of the 115 patients who reached the 5-year visit, the uncorrected distance visual acuity (UDVA) was 20/40 or better in 86,4% of patients and 20/25 or better in 50% of patients. The corrected distance visual acuity (CDVA) was 20/32 or better in 95.45% of patients and 20/20 or better in 81.82% of patients. Five years after implantation, the mean endothelium-IOL distance was 1.86 ±0.56 mm and mean IOL-cryistalline distance 0.97±0.37 mm. Mean percentage of endotehlial cell loss was 3,46% at five years and the coefficient of variation in cell size decreased from 39.13 before surgery to 31.39 at 5 years after implantation. The mean value of internal total HOAs was 0.43±0.13 μm, internal primary spherical aberration was -0.27±0.17 μm and internal primary coma was 0.17±0.46 μm.


Five-years findings showed that the Acrysof Cachet pIOL provided favorable refractive correction and predictability and acceptable safety in patients with moderate to high myopia and maintained adequate central clearance distances to the corneal endothelium and the natural lens. FINANCIAL INTEREST: NONE

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