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Radiation-related lens density changes and cataract formation in patients udergoing CyberKnife robotic radiosurgery

Poster Details

First Author: D.Tarnawska POLAND

Co Author(s):    M. Orski   E. Wylegala           

Abstract Details



Purpose:

The aim of our study was to assess 6 - month radiation - related lens density changes and cataract formation in patients udergoing CyberKnife Robotic Radiosurgery for the treatment of central nervous system lesions.

Setting:

CyberKnife Robotic Radiosurgery System enables delivery of beams of high dose radiation with extreme accuracy. Ocular side effects after radiation therapy have been reported and include cataract formation.

Methods:

We examined 28 patients undergoing CyberKnife Robotic Surgery for meningiomas located close to optic chiasm in order to assess effects of radiation on lens and cataract formation. Patients received 18 Gy in 3 fractions. Doses delivered to optic tract were on average 15 Gy in 3 fractions. Slit lamp biomicroscopy with dialated fundus exam, Best Corrected Visual Acuity (BCVA), and assessment of cataract formation using grading system by Scheimpflug imaging (Oculus Pentacam Nucleus Grading System [PNS]) were obtained at a baseline and six months after radiotherapy.

Results:

No pathological changes in slit lamp examination with dialated fundus exam were revealed. No significant cataract formation or progession was observed. No statistically significant changes in BCVA was noted (p>0,05 Wilcoxon paired test).

Conclusions:

Our study did not show any significant inluence of radiation on cataract formation in patients treated with CyberKnife Robotic Radiosurgery for brain lesions in six month follow up period. Further observation of potential radiation - related ocular influence and complications is required. FINANCIAL INTEREST: NONE

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