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Conjunctival squamous cell carcinoma: two aggressive cases

Poster Details

First Author: R.Manescu ROMANIA

Co Author(s):    S. Craitoiu   M. Niculescu   A. Balasoiu   C. Mocanu   D. Barascu   C. Olaru

Abstract Details



Purpose:

The authors present two very aggressive cases of squamous - cell conjunctival carcinomas, hospitalized in the Ophthalmology Clinic in the last two years.

Setting:

Conjunctival squamous cell carcinoma is a rare tumor. It is frequently situated juxtalimbal and may involve adjacent cornea. It may rarely arise from forniceal conjunctiva.

Methods:

The cases presented are: a 75 year old female patient, from the countryside, with a conjunctival limbic squamous - cell carcinoma and a 59 year old male, also from the countryside, with a conjunctival squamous - cell carcinoma away from the limbus, but with caruncular invasion.

Results:

Both tumors were excised in oncologic surgical limits. The histopathological exam confirmed the malignant clinical aspect of the tumors. Oncologic treatment (chemotherapy and radiotherapy) was performed. After two years of oncologic and ophthalmological survey, both cases presented orbital invasion with indication for exenteration. No distance methastasis were detected at neither one of the patients.Conjunctival squamous cell carcinoma presents the following risk factors: sun exposure, papilloma virus and HIV diseases, pre-existing / previous conjuctival benign lesions. Clinical manifestations are variable and they depend on the tumor evolutive stage displaying aspects of benign lesions that could lead to a late diagnosis and surgical treatment.

Conclusions:

Conjunctival squamous - cell carcinomas have invasive local potential but also at the distance. Early diagnosis and surgical treatment but also the active oncologic survey may improve the prognosis. Sometimes, in spite of active oncologic and ophthalmologic survey, exenteration is the only solution. FINANCIAL INTEREST: NONE

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