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Profile of the ocular dimensions, interocular asymmetry and their associations in an older white population: the Edinburgh eye study

Poster Details

First Author: Y.Neo UK

Co Author(s):    B. Dhillon              

Abstract Details


To describe the distribution, and association of ocular dimensions and interocular asymmetry with adult stature and sociodemographic status.


Princess Alexandra Eye Pavilion, Edinburgh, Scotland, UK.


This was a population based cross-sectional study of adult Caucasians with cataract aged ≥50 in Edinburgh, Scotland. Data were available for 231 males and 279 females with phakic eyes. Axial length (AL), corneal curvature (Km) and anterior chamber depth (ACD) were measured using partial coherence laser interferometry as part of preoperative assessment. Interocular biometric asymmetry was recorded as an absolute value of difference between both eyes. Scottish Index of Multiple Deprivation (SIMD) was used to estimate patients' sociodemographic status. A comparative analysis of the mean values for male and female was performed. Multivariate linear regression models were constructed to examine the effect of height, weight, SIMD (explanatory factors) on the ocular biometric components and their respective interocular asymmetry, controlling for age and gender.


Females generally have steeper corneal profile (Km =44.1D) than males (Km =43.95D) (p<0.001). Mean AL (23.8mm) and ACD (3.04mm) were both higher in male than female (AL=23.2mm; ACD=3.04mm) (p<0.001). Interocular asymmetry in all AL, Km and ACD were higher in females (p<0.001). Height, weight and SIMD demonstrated significant positive correlation with AL (p<0.001) but do not appear to have an influence on the ACD. Taller and heavier persons were found to have a flatter cornea profile of less convex dioptric power. Height independently showed significant negative correlation with interocular Km asymmetry (p<0.001).Weight and SIMD demonstrated no correlation with interocular asymmetry of the ocular dimensions.


In this population, longer AL was found in taller, heavier and more affluent adults. Taller and heavier persons were found to have a flatter cornea profile of less convex dioptric power. ACD was free from the influence of adult stature and sociodemographic status. Increased height was independently related to lesser degree of corneal astigmatism. Findings suggest strong environmental determinants for AL, Km and ACD, but not the interocular asymmetry of these ocular dimensions. FINANCIAL INTEREST: NONE

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