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Short-term refractive change and ocular parameter changes after cycloplegia

Poster Details

First Author: H.Cheng TAIWAN

Co Author(s):    Y. Hsieh              

Abstract Details


To explore short term refractive and ocular parameter changes and their correlations after cycloplegia with tropicamide.


Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, TAIWAN


This study prospectively enrolled 114 right eyes of 114 participants. Spherical equivalent of refractive error (SER), axial length (AL), corneal curvature (CC), and anterior chamber depth (ACD) were measured before and after 30 minutes from instillation of 0.4% tropicamide. Refractive change and ocular parameter changes after cycloplegia and their correlations were evaluated.


SER, AL, and ACD all positively shifted significantly at 30 minutes following application of 0.4% tropicamide (p < 0.0001 for each parameter measured). After cycloplegia, 28 eyes (24.6%) had a hyperopic shift of more than 0.25 D, 3 eyes (2.6%) had a myopic shift of more than 0.25 D, and 83 eyes (72.8%) had their SER changes within -0.25 D to 0.25 D. The mean, maximum, and minimum keratometric values all decreased (p = 0.005, 0.03, and 0.05, respectively), while corneal astigmatism did not change significantly. The changes in AL, ACD, or mean keratometric values contributed to the refractive changes after cycloplegia by tropicamide (p > 0.05, pr2 ≤ 0.01 for all values).


SER, AL and ACD all positively shifted after cycloplegia with tropicamide. After 30 minutes from topical instillation of 0.4% tropicamide, the axial length increased, the anterior chamber was deepened and the refraction had hyperopic shift. CC became flattened after cycloplegia with tropicamide, but the corneal astigmatism did not change significantly. Refractive changes correlated with AL, ACD or CC changes after cycloplegia with tropicamide. FINANCIAL INTEREST: NONE

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