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Paralysis of cranial nerves III, IV and VI: causes and prognosis in 96 cases

Poster Details

First Author: N.Aghadoost IRAN

Co Author(s):    D. Aghadoost   H. Aghadoost           

Abstract Details


To report causes and prognosis of cranial nerve palsies 3, 4 and 6 in an ophthalmology clinic.


Matini Hospital, Amirkabir ave. Kashan, Iran


In a cross-sectional case studies during April 2004- December 2005, 96 cases of cranial palsy 3, 4 or 6th enrolled in this study in an ophthalmology clinic. All patients underwent detailed ocular and neurologic examination and needed paraclinic tests and neuroimaging (CT-Scan or MRI). All patients followed at least for 6 months.


Mean age of patients was 50.5 years (range 8 to 80 years). Sixty-nine percent of patients were male. The frequency of involvement of the third, fourth and sixth cranial nerves was 34.4%, 15.6% and 47% respectively. In 3% of cases more than one cranial nerve involved. Mean follow up of patients was 14 months (range 6 to 24 months). In 85.4% of cases spontaneous recovery occurred. The most common causes of cranial nerve impairment was microvascular diseases (diabetes mellitus, hypertension) in 66.7% and trauma in 26.4% regardless of affected cranial nerves. In 48% of traumatic cases cranial nerve palsy became permanent.


Cranial nerve palsies due to microvascular diseases has higher chance of spontaneous recovery in relation to other causes such as trauma or malignancies. FINANCIAL INTEREST: NONE

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