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15 years follow-up of photorefractive keratectomy up to 10 diopters of myopia and 4.5 diopters of astigmatism

Poster Details


Co Author(s):    F. Soria   P. Peña-Garcia   J. Alio   A. Alessandro     

Abstract Details


To evaluate outcomes of photorefractive keratectomy (PRK) in myopia up to -10.00D and develop a predictive model for the refractive changes in the long-term.


Vissum Corporation and Miguel Hernandez University (Alicante, Spain)


This retrospective-prospective, observational, consecutive series of cases included 33 eyes of 33 patients aged 46.79±7.04 (range 39 to 54) operated with the VISX 20/20 excimer laser with optical zones of 6mm. The minimum follow up was 15 years. The main outcome measures were: uncorrected and corrected distance visual acuity (UDVA, CDVA), manifest refraction and corneal topography. Linear regression models were developed to predict refractive changes.


Safety and efficacy indexes at 15 years were 1.18 and 0.83 respectively. No significant differences were detected for any keratometric variable during the follow up (p≥0.103). 15 years after the surgery 54.55% of the eyes were within ±1.00D of spherical equivalent (SE) and 84.85% within ±2.00D. The UDVA at 15 years was 20/30 or better in 60.6% of the eyes and 20/40 or better in 72.73% of the eyes. The correlation between the attempted and the achieved refraction was r=0.948 (p<0.001) at 1 year, and r=0.821 (p<0.001) at 15 years. No corneal ectasia was detected in any case during the follow up.


PRK is a safe refractive procedure in the long-term within the range of myopia currently considered suitable for its use, although its efficacy decreases with time, especially, in high myopia. The model developed predicts a myopic regression of 2.00 diopters at 15 years for an ablation depth of 130µm. FINANCIAL INTEREST: NONE

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