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The influence of cationic nanoemulsion on the tear film stability in patients after photorefractive keratectomy

Poster Details

First Author: E.Mrukwa-Kominek POLAND

Co Author(s):    A. Orlicka-Mosiej   B. Bubala-Stachowicz   M. Sarnat   P. Kucharzewski   E. Filipek   M. Szymanska

Abstract Details



Purpose:

The assessment of the influence of new technologies on the tear film stability, corneal epithelium condition, optical aberrations as a function of vision in patients after photorefractive keratectomy

Setting:

1Department of Ophthalmology, 2University Centre of Ophthalmology and Oncology Silesian University of Medicine, Katowice, Poland

Methods:

Photorefractive keratectomy was performed in 20 patients in 40 eyes with myopia and myopic astigmatism, divided in two groups: group I - 20 eyes where cationic nanoemulsion Cationorm (Santen Oy) was administered 4 times daily and group II - 20 eyes where the preservative free artificial tears administered 4 times daily. Both groups were statistically consistent as to sex, age and refractive errors corrected. All patients were examined: 7 days, 3 weeks, 6 weeks and three months after surgery. There were assessed changes in: UCVA, BCVA, mean spherical equivalent, keratometric values, optical aberrations, fluorescein tear film break-up time (fTBUT). The efficacy of the treatment was determined on the basis of the tear film stability and patients subjective symptoms

Results:

There were no statistically significant differences between groups in postoperative visual acuity, mean spherical equivalent, mean keratometric values. Changes were observed in corneal aberration. Statistically significant differences were found in evaluating tear film stability in favor of the group I 6 weeks after surgery (p<0.05). Epitheliopathy and dryness was not observed in group I while 2 patients (4eyes) in group II experienced dryness longer than one month after surgery. During the postop time patients subjective symptoms changed significantly in group I (p<0.05) and not significantly in group II (p>0.05).

Conclusions:

The use cationic nanoemulsion after photorefractive keratectomy is a reasonable due to the efficient tear film stability, and improvement of subjective satisfaction especially in the early postoperative period FINANCIAL INTEREST: One of more of the authors... travel has been funded, fully or partially, by a competing company

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