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Comparison of anterior segment OCT parameters between central retinal vein occlusion and normal eyes: is primary angle closure a risk factor for central retinal vein occlusion?

Poster Details

First Author: M.Mohammadi IRAN

Co Author(s):    F. Bazvand   A. Mokateb   Y. Eslami   M. Jabbarvand Behrooz   S. Moghimi  

Abstract Details



Purpose:

to compare anterior segment parameters in the patients with central retinal vein occlusion (CRVO) with normal control subjects by anterior segment optical coherence tomography (AS-OCT).

Setting:

Farabi Eye Hospital, Department of Ophthalmology, Tehran University of Medical Sciences,Tehran, Iran

Methods:

42 eyes from 21 patients with unilateral CRVO and 21 eyes from 21 age and sex match healthy control subjects were recruited in this study. Study eyes were divided into three groups as follows: involved eye of CRVO patients(CRVO eyes), fellow eye of CRVO patients (fellow eyes) and control eyes. Complete ocular examination including gonioscopy and AS-OCT were performed for each eye. The AS-OCT parameters(anterior chamber depth [ACD],scleral spur angle[SSA],angle opening distance at 500μm and 750μm from scleral spur [AOD500 and 750] and trabecular-iris space area at 500μm and 750μm from scleral spur [TISA500 and 750]) and the rate of angle closure in CRVO and fellow eyes were compared with control eyes.

Results:

The mean(SD) age of the patients and the control group was 60.09(9.43) and 59.52(6.66). There was 13 female and 8 male in each group. Mean intraocular pressure (IOP) in both eyes of patients was significantly higher than control eyes (15.2mmHg and 15.8mmHg versus 12.8mmHg, p=0.005 and 0.011, respectively). Comparing with control eyes, CRVO eyes had shallower ACD[2.53mm vs. 2.85mm, p=0.002] and narrower AS-OCT angle parameters(SSA, AOD500 and 750, TISA 500 and 750). Fellow eyes had also shallower ACD(2.56mm vs. 2.85mm, p=0.005) than control eyes and smaller SSA, AOD500 and AOD750. According ti gonioscopic examination results 5 (23.8%) CRVO patients were diagnosed with angle closure in both eyes ,whereas no eye in the control group had angle closure(p=0.05).

Conclusions:

Imaging with AS-OCT showed that CRVO patients had shallower ACD and narrower angle parametes in both eye in comparison with control eyes. Furthermore, CRVO patients had higher rates of angle closure on gonioscopic examination. These findings suggest that angle closure may be a risk factor for CRVO. FINANCIAL INTEREST: NONE

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