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A comparison of efficacy and safety according to the range and position in selective laser trabeculoplasty (SLT)

Poster Details

First Author: Y.Yun SOUTH KOREA

Co Author(s):                  

Abstract Details



Purpose:

To compare the intraocular pressure-lowering effect and safety according to the range and position in Selective Laser Trabeculoplasty(SLT)

Setting:

IYUN EYE Hospial.

Methods:

In a retrospective clinical study, the authors compared the pressure-lowering effects of SLT in three groups of patients; group 1 (30 patients) received SLT on 90°, group 2 (30 patients) on 180° and group 3 (30 patients) on 360°of trabecular meshwork. The clinical outcome indicators included intraocular pressure (IOP) at one day, one week, one month, two months, three months and six months after SLT, and the anterior chamber reaction at post-laser one day. Eighty patients with primary open-angle glaucoma and normal tension glaucoma were treated 20 patients with superior 180-degree SLT, 20 patients with the same diagnosis were treated with inferior 180-degree SLT, 20 patients with the same diagnosis were treated nasal 180-degree SLT, 20 patients the same diagnosis were treated with temporal 180-degree SLT. IOP was checked at 1 day, and 1, 2, 3, and 6 months after SLT. Anterior chamber reaction and ocular pain was evaluated at postoperative 1 day. Peripheral anterior synechia was examined at 6 months postoperatively.

Results:

There was no statistically significant difference in the IOP reduction between these two regimens(180° and 360°) after six months. The anterior chamber reactions in the two groups were significantly different (group 1; 0.61 ± 0.64, group 2; 1.25 ± 0.83, p = 0.001). The success rate of group 3 (43.3%) was not different from that of group 2 (31.3%; p = 0.23). But the success rate of group 1(90°) was lower than in the other groups(2, 3) At the postoperative 6-month follow-up, the superior treatment group had a mean IOP of 15.53 ± 3.49 mm Hg with a mean reduction of 24.6%, the inferior treatment group had a mean IOP of 17.18 ± 3.29 mm Hg with a mean reduc- tion of 21.9%, the nasal treatment group had a mean IOP of 16.58 ± 2.28 mm Hg with a mean reduc- tion of 23.8% and the temporal treatment group had a mean IOP of 17.02 ± 2.39 mm Hg with a mean reduc- tion of 24.1%. There were no significant differences in IOP reduction Between 4 groups. There was a slightly higher an- terior chamber reaction rate in the inferior treatment group.

Conclusions:

The site of SLT application is not important for IOP reduction. Between superior, inferior, nasal and temporal 180 degree SLT are safe and effective procedures for glaucoma treatment because of successful IOP reduction and low complication risks and suggest that 180° SLT is the safest procedure with regard to success rate and complications. FINANCIAL INTEREST: NONE

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