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Initial laboratory evaluation of a novel technique: flap-less, femtosecond laser-assisted myopic refractive lens extraction, stabilized with high-fluence CXL

Poster Details

First Author: A.Kanellopoulos GREECE

Co Author(s):    G. Asimellis   I. Kontari           

Abstract Details



Purpose:

To evaluate feasibility of ex-vivo femto-second laser-assisted intra-lamellar refractive lens extraction (ReLeX) using a novel technique with an alternative femtosecond-laser.

Setting:

Laservision.gr Eye Institute, Athens, Greece

Methods:

Two-surface intra-lamellar bed corneal dissections were performed within a 5.5 mm optical zone. Lower. The FS200 femtosecond laser (Alcon/WaveLight, Erlangen, Germany) was employed in the study involving cadaver corneas. The lenticule was extracted through a 3.5 mm wide superior canal. High-fluence CXL was conducted in the pocket created. Pre- and post-operative total and lenticule thickness were measured by means of anterior-segment optical coherence tomography. Pre and post-operative corneal curvature was investigated via Scheimpflug imaging. Maximum (central) corneal thickness differences were compared to Munnerlyn formula predictions.

Results:

Lenticule creation and secondary extraction through the superior canal was efficient when employing the FS200 laser. Lenticule thickness studied was that of 50 μm. OCT-derived corneal thickness differences, as well as Scheimpflug imaging-derived topographic differences were consistent with a myopic change. Both modalities highlighted the interlamellar CXL effect.

Conclusions:

This ex-vivo laboratory study confirms the FS200 femtosecond laser refractive lens extraction capability for correcting myopia. In-pocket adjunct cross-linking may facilitate, stabilize the postoperative recovery, and potentially be employed to induce asphericity and correct small residual spherocylindrical refractive errors. FINANCIAL INTEREST: One of more of the authors... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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