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Use of combined biomechanical and tomographic data to detect keratoconus

Poster Details

First Author: E.Guilbert FRANCE

Co Author(s):    A. Saad   A. Grise-Dulac   H. Rouger   M. Humeniuk   D. Gatinel  

Abstract Details


To determine a new index using combined corneal biomechanical and tomographic data helping to detect keratoconus


Fondation Ophtalmologique Adolphe de Rothschild, Paris, France


Data of 213 eyes separated into two groups were retrospectively reviewed : normal (n=109) and keratoconus (n=104). Corneal hysteresis (CH), corneal resistance factor (CRF) and other biomechanical parameters were measured with an ocular biomechanics analyzer. Corneal thickness was measured using a combined placido-scanning slit system.


Using CH, CRF, H1, thinnest point and central corneal thickness, our index was able to discriminate normal cornea from keratoconus with a sensitivity of 96.2 % and a specificity of 90.8 %. ROC curve showed an area under curve of 0.967.


Sensitivity and specificity of our new index combining biomechanical and tomographic data were high in detecting keratoconus. FINANCIAL INTEREST: NONE

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