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Sex hormone levels and corneal hysteresis during menstrual cycle

Poster Details

First Author: A.Bakhtiari MALAYSIA

Co Author(s):    V. Subrayan              

Abstract Details


To determine corneal ocular hysteresis change during phases of the menstrual cycle and to correlate with sex hormone levels.


University Malaya Medical Center


31 eyes of 31 healthy young women (18-27 years old) were recruited. Hormones including follicle stimulating hormone (FSH; mU/ml), luteinizing hormone (LH; mU/ml), progesterone (ng/ml) and 17-β estradiol (pg/ml) were measured in serum three times in a cycle during the follicular (day 3 to day 9), luteal phases (day 21 to day 28) and ovulation (day 13 to day15). At every time point, corneal hysteresis (CH) were measured with the Ocular Response Analyzer.


The mean corneal hysteresis values at follicular, ovulatory, and luteal phases were 12.8mm Hg, 11.7mm Hg, and 12.4 mmHg (p < 0.05), There was a reverse correlation between serum estradiol and CH (Pearson correlation=-0.28, P=0.039)


The corneal hysteresis is a bimechanical property of the cornea that changes during a menstrual cycle that might be due to serum estradiol levels. FINANCIAL INTEREST: NONE

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