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Sex hormone levels and corneal hysteresis during menstrual cycle

Poster Details

First Author: A.Bakhtiari MALAYSIA

Co Author(s):    V. Subrayan              

Abstract Details



Purpose:

To determine corneal ocular hysteresis change during phases of the menstrual cycle and to correlate with sex hormone levels.

Setting:

University Malaya Medical Center

Methods:

31 eyes of 31 healthy young women (18-27 years old) were recruited. Hormones including follicle stimulating hormone (FSH; mU/ml), luteinizing hormone (LH; mU/ml), progesterone (ng/ml) and 17-β estradiol (pg/ml) were measured in serum three times in a cycle during the follicular (day 3 to day 9), luteal phases (day 21 to day 28) and ovulation (day 13 to day15). At every time point, corneal hysteresis (CH) were measured with the Ocular Response Analyzer.

Results:

The mean corneal hysteresis values at follicular, ovulatory, and luteal phases were 12.8mm Hg, 11.7mm Hg, and 12.4 mmHg (p < 0.05), There was a reverse correlation between serum estradiol and CH (Pearson correlation=-0.28, P=0.039)

Conclusions:

The corneal hysteresis is a bimechanical property of the cornea that changes during a menstrual cycle that might be due to serum estradiol levels. FINANCIAL INTEREST: NONE

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