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Correlations between corneal biomechanics and corneal Pentacam measured parameters

Poster Details

First Author: M.Abrishami IRAN

Co Author(s):    M. Sedaghat              

Abstract Details


To evaluate the relationship between corneal hysteresis (CH) and corneal resistance factor (CRF), and corneal parameters in normal young Iranian population subjects.


Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran


In an observational cross-sectional study, volunteer subjects aged 18-35 years were included. Exclusion criteria were history of any intraocular or corneal disease, anomaly or surgery; hyperopic spherical refraction more than +3.00 diopters (D), and myopic spherical refraction less than -5.00 D or cylindrical refraction more than 2.50D. Ocular Response Analyzer was used to measure CH and CRF. Corneal volume (CV), anterior and posterior Q value (QA and QP), anterior and posterior elevation (AE and PE), central corneal thickness (CCT), and corneal thinnest thickness (CTT) were measured with Pentacam. Descriptive analysis, and Pearson correlation test were used for statistical analysis.


This study evaluated 408 eyes of 204 cases (126 females) with a mean age of 28.43 ± 6.36 years. The average CH and CRF were 10.07±1.61 and 10.33±1.68 mmHg. CH and CRF were not correlated to PQ, AQ, AE and PE. CH and CRF were significantly correlated with CCT (r=0.499, p<0.0001 and r=0.591, p<0.0001 respectively), CTT (r=0.469, p<0.0001 and r=0.593, p<0.0001 respectively) and CV (r=0.443, p<0.0001 and r=0.526, p<0.0001 respectively).


A significant positive correlation was found between CH and CRF, and CCT, CTT and CV. This study also provided information about wide range normative values of corneal parameters in the anterior segment of healthy young Iranian eyes. Corneal biomechanical measures may prove valuable for qualification and predictions of outcomes of refractive surgery. FINANCIAL INTEREST: NONE

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