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Peripheral corneal thickness after penetrating keratoplasty as a prognostic factor of grafted cornea

Poster Details

First Author: M.Park SOUTH KOREA

Co Author(s):    H. Yang   J. Hwang   M. Kim        

Abstract Details


To evaluate the correlation between prognosis of grafted cornea and peripheral corneal thickness after penetrating keratoplasty.


Department of Ophthalmology and Visual Science, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea


We performed retrospective chart review about 111 eyes of 111 pateints who underwent penetrating keratoplasty from Oct. 2010 to Dec. 2013. Peripheral corneal thickness at 4 mm away from the center at 4 directions (12o/c, 3 o/c, 6 o/c, 9 o/c) were measured by using scanning-slit pachymetry at postoperative 1 year and averaged. We classified 111 eye`s by three groups according to peripheral corneal thickness, and compared and analyzed prevalence of graft failure after penetrating keratoplasty at each groups


The 40 eye`s of 111 eye`s were classed as thin peripheral cornea thickness group (averaged peripheral corneal thickness≤ 700㎛), 38 eye`s were classed as moderate peripheral corneal thickness group(averaged peripheral corneal thickness, 700 to 800㎛), 33 eye`s was classed as thick peripheral corneal thickness group(averaged peripheral corneal thickness> 800㎛). Prevalence rate of graft failure was 17.5% (7 eye`s) at thin thickness group, 13.2% (5eye`s) at moderate thickness group, 15.2%(5 eye`s) at thick thickness group. 2 year survival rate was 83.5% at thin thickness group, 81.5% at moderate thickness group, 77.6% at thick thickness group and there was no statistically significant difference among three groups (P=0.897). And in ROC curve, peripheral corneal thickness was not a important factor to predict and diagnosis graft failure.


There was no significant correlation between postoperative averaged peripheral corneal thickness and function of grafted cornea. But further research is needed into long-term postoperative complications related to thickened peripheral cornea FINANCIAL INTEREST: NONE

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