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Endothelial cell counts and final visual acuity in complex DSEK

Poster Details

First Author: C.MacGregor UK

Co Author(s):    M. Tsatsos   P. Hossain   D. Anderson        

Abstract Details



Purpose:

To evaluate the visual outcomes and endothelial cell numbers in complex cases of DSEK

Setting:

Southampton University Hospital

Methods:

Retrospective analysis of 23 consecutive DSEK cases over 44 months that were deemed as complex due to pre-existing pathology. SPSS software was used. Patients were examined clinically at 1,3,6,9 and 12 months post-operatively where best corrected visual acuity (BCVA) and anterior segment optical coherence tomography (AS-OCT) were measured at these intervals. Patients underwent spectral microscopy at 12 months post-operatively.

Results:

23 cases were identified as complex. 30% were due to pre-existing corneal pathology, 30% of cases were due to aphakia, 40% of identified cases were due to graft detachments or previous DSEK graft failures. Mean donor endothelial cell count was 2570. Mean 12-month post-operative endothelial cell count was 1326 (reduction of 51.6%). Mean pre-operative BCVA was 1.48 LogMar. Mean post-operative BCVA at 12 months was 0.58 LogMar.

Conclusions:

DSEK undertaken in this patient group lead to greatly improved BCVA while maintaining a sufficient number of endothelial cells. FINANCIAL INTEREST: NONE

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