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Viscoelastic-assisted non-Descemet's stripping automated endothelial keratoplasty in vitrectomized and iris-lens diaphragm injured eyes

Poster Details

First Author: W.Chen CHINA

Co Author(s):    Y. Ren   Z. Zhao   V. Jhanji        

Abstract Details


To report a modified technique of viscoelastic-aided non-Descemet stripping automated endothelial keratoplasty (nDSAEK) to treat bullous keratopathy in vitrectomized and iris-lens diaphragm injured eyes.


Prospective consecutive case series study.


A prospective consecutive case series of eyes with bullous keratopathy underwent nDSAEK. A minimum effective volume of cohesive viscoelastic was injected into the anterior chamber in front of the iris defect to prevent air from entering the posterior chamber and vitreous avity. Filtered air was injected until the intraocular pressure (IOP) rose to a mildly high level. Graft position, IOP, and complications were monitored postoperatively. Endothelial cell density and best-corrected visual acuity (BCVA) were recorded at 1-year follow-up.


Effective graft adherence was achieved in all cases intraoperatively. Postoperatively, partial graft dislocation was seen in 2 cases due to hypotony that was successfully managed conservatively. One year postoperatively, the median BCVA improved to 20/50, and the endothelial cell loss averaged 20.5±11.1%.


In vitrectomized and iris-lens diaphragm injured eyes, the modified viscoelastic- aided nDSAEK effectively facilitated graft adherence and reduced graft dislocation. Appropriate control of IOP was considered to play a vital role in supporting the graft adherence. FINANCIAL INTEREST: NONE

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