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Descemet's stripping endothelial keratoplasty (DSEK): complication rates in 100 consecutive cases at a tertiary university hospital

Poster Details

First Author: N.Abdul Aziz UK

Co Author(s):    M. Rashid   P. Hossain           

Abstract Details



Purpose:

The purpose of this study is to describe the outcome and complications of DSEK surgery using manually dissected donor tissue at a tertiary university referral centre.

Setting:

University Hospital of Southampton NHS Trust, Southampton Eye Unit, Mailpoint 104, Tremona Road, Southampton, Hants, SO16 6YD

Methods:

A retrospective, consecutive case review of 100 eyes between 2007 and 2013. Main outcome measures included best corrected distance visual acuity (BDVA), post-operative manifest refractive spherical equivalence (MRSE), IOP elevation, and posterior graft dislocation, graft rejection, primary graft failure, and graft survival rates at 24 months.

Results:

The mean (SD) age at the time of surgery was 72±12.6 years. Surgical indications included Fuch's dystrophy (68%), bullous keratopathy (30%) and previous failed graft (20%). Thirty-two percent were pseudophakic and 15% were phakic eyes. Eighty-five percent had DSEK alone, 6% had repeat DSEK and 8% received a triple procedure. Raised IOP was the main complication (49%), followed by posterior graft dislocation (14%), graft rejection (8.5%) and primary graft failure (4%). Mean (SD) LogMAR BDVA was 0.7±0.5 and 0.5±0.3 at 12 and 24 months, respectively. The average post-operative MRSE at last review was 0.9±0.7D. Rate of graft survival at 24 months was 82%.

Conclusions:

The main complication observed at our centre was raised IOP. Posterior graft dislocation, graft rejection and primary graft failure rates were comparable to those reported elsewhere in the peer-reviewed literature. FINANCIAL INTEREST: NONE

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