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Corneal melanosis: a four-year survey

Poster Details

First Author: M.Balcı TURKEY

Co Author(s):    R. Yağci   E. Güler   H. Altaş   R. Duman   I. Hepşen  

Abstract Details


To report a case of corneal primary acquired melanosis (PAM) without atypia in a patient with a history of limbal malignant melanoma


Dr.Abdurrahman Yurtaslan Oncology Training and Research Hospital


A 75-year-old woman with a history of limbal malignant melanoma presented with loss of vision in her right eye. Slit-lamp examination showed a patchy melanotic pigmentation that covered the upper nasal limbal quadrant, periphery, and midperiphery of the cornea without any corneal vascularization. Additionally, a central corneal haze was seen in the same eye.


After the application topical mitomycin-C (MMC), the visual acuity improved, and the corneal haze disappeared. However, the pigmented lesions persisted, and we excised the corneal epithelium and underlying pigmented layer with alcohol epitheliectomy. Histopathologic examination demonstrated PAM without atypia. The lesions were successfully removed, and there were no recurrences during the followup period of 48 months


We present this case to illustrate the association of conjunctival and corneal melanosis without atypia which is a rare condition. Another point is the coexistence of central corneal haze and melanosis, which were considered to decrease the best corrected visual acuity. Topical MMC and alcohol-induced corneal epitheliectomy can be useful treatments in this situation. FINANCIAL INTEREST: NONE

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