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Prospective comparative clinical trial of a heparin-modified single-piece intraocular lens (IOL) of hydrophobic acrylate to an identical control IOL without coating

Poster Details

First Author: E.Krall AUSTRIA

Co Author(s):    G. Jell   E. Arlt   C. Strohmaier   A. Bachernegg   G. Grabner   A. Dexl

Abstract Details


To compare posterior capsule opacification (PCO) of a hydrophobic acrylic IOL with heparin modified surface (Polylens Y10AS; HC-IOL) compared to the same IOL without heparin coating (EC-1Y-PAL; UC-IOL) one year postoperatively.


Paracelsus Medical University Salzburg, Austria - Department of Ophthalmology


102 eyes of 51 patients underwent routine phacoemulsification with randomized implantation of HC-IOL in one eye and UC IOL in the fellow eye. The morphologic evaluation of PCO was performed comparing digital photographs in retroillumination using EPCO (Evaluation of Posterior Capsule Opacification) system. Additionally distance visual acuities and subjective manifest refraction, pupil size, straylight measurements (C-Quant), flare in the anterior chamber using a laser flare meter (FM-600), mesopic and photopic, contrast sensitivity (Optec 6500P Vision Tester) were evaluated.


No statistically significant differences neither in EPCO score (p=0.25) nor in EPCO area in the HC-IOL group compared to the UC-IOL group could be seen. Furthermore, no statistically significant differences were detected in the secondary outcome parameters - straylight measurement, distance visual acuities, flare in the anterior chamber, pupil size and mesopic and photopic contrast sensitivity - comparing both IOL types.


No significant difference in PCO could be determined between both IOL types. FINANCIAL INTEREST: NONE

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