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Post-phacoemulsification NSAIDs in diabetic patients

Poster Details

First Author: I.Elhawary SAUDI ARABIA

Co Author(s):                  

Abstract Details



Purpose:

To study the progression of retinal changes following cataract surgery in diabetic patients with normal fundus or mild NPDR treated post-operatively with topical steroids alone compared to topical steroids and topical NSAIDS.

Setting:

Magrabi Eye Hospital

Methods:

Retrospective review of patients with diabetes with either mild NPDR (without maculopathy) or no retinopathy, who underwent uneventful phacoemulsification from May 2011 to July 2013. Patients with maculopathy or other fundus pathology were excluded. Patients were catagorised into: Group 1: Patients on topical steroids and topical NSAIDS. Group 2: Patients on topical steroids only. Patients' demographics, best corrected visual acuity pre-operatively, 3 and 6 months post-operatively, grade of diabetic retinopathy and maculopathy pre and 3-6 months post-operatively were collected.

Results:

90 eyes in group 1 and 94 eyes in group 2 fulfilled inclusion criteria. Male: female ratio was 1.7:1 in group 1 and 1.2:1 in group 2. Age range was 49-82 years in group 1 and 48-79 years in group 2. In group 1, 31% had NPDR and 69% had no retinopathy. In group 2, 43% had NPDR and 57% had no retinopathy. Progression of diabetic retinopathy was noted in 2/90 eyes (2.2%) in group 1 and 2/94 eyes (2.1%) in group 2. In group 1, 3/90 eyes (3.3%) and group 2, 3/94 (3.2%) developed clinically significant macular oedema within 6 months of phacoemulsification

Conclusions:

In this study no difference was found in the incidence of progression of diabetic retinopathy and maculopathy in diabetic patients with mild NPDR or no diabetic retinopathy post phacoemulsification in patients treated with topical steroids only compared to those treated with topical steroids and topical NSAIDs. Therefore addition of a topical NSAID may not be beneficial in this group of patients. FINANCIAL INTEREST: NONE

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