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Outcomes in cataract surgery: high-cost versus low-cost single-piece hydrophobic intraocular lens implantation in phacoemulsification - a contralateral eye study

Poster Details

First Author: S.Basak INDIA

Co Author(s):    S. Mitra              

Abstract Details


Hydrophobic acrylic Intraocular lens (IOL) is gold standard in terms of material biocompatibility, safety and long-term outcomes. In India many companies are now manufacturing low-cost hydrophobic IOL which is relevant for the developing world. The purpose of this study was to compare the cost and outcomes of high-cost and low-cost hydrophobic single-piece IOL implantation in phacoemulsification.


Disha Eye Hospitals & Research Centre, Kolkata, West Bengal; 700120, India.


This was a prospective non-randomized contralateral eye study. 148 patients underwent sequential bilateral cataract surgery with a gap of 2- 4 weeks between two eyes. One eye (Group A) was with high-cost hydrophobic single-piece IOL (AcrySof SA60AT) and other eye (Group B) with a low-cost hydrophobic single-piece IOL (Aurovue; HP7600). All surgeries were performed by stop and chop technique by the same surgeon. Eye with any complication during surgery was excluded from this study. Follow up by a masked examiner after 1 week, 3 months, 12 months and 24 months for anterior chamber reactions; best spectacle corrected visual acuity (BSCVA), IOL centration; and incidence of posterior capsular opacification (PCO) at the end of 24 months follow-up. Cost of the IOL in each group was taken into account.


Two eyes in two patients had operative complications and excluded from this study. 146 patients were enrolled and all of them completed 1 week follow up. 140 (95.8%) patients completed 3 months, 120 (82%) completed 1 year and 101 (69.1%) patients completed 2 years follow-up. No significant difference was found between the two groups (p>0.05) in terms of anterior chamber reactions, BSCVA, amount in IOL decentration at 1 week and 3 months postoperative follow ups. Significant PCO with loss of two line occurred in 1 eye in Group A and 2 eyes in Group B after 1 year (P<0.05). At the end of two years 4 eyes in each group developed significant PCO with loss of two lines requiring YAG capsulotomy. The cost of high-cost hydrophobic IOL was 4.5 times higher (20 USD vs 92 USD) in Indian market.


Low-cost single-piece hydrophobic IOL (Aurovue: HP7600) is a very good alternative to high-cost single-piece hydrophobic IOL (AcrySof: SA60AT) in terms of safety, anterior chamber reaction, IOL centration and postoperative visual outcomes. PCO formation is almost similar in both groups at the end of one and two years follow-up. When affordability is an issue, the phacoemulsification with HP7600 IOL is much more acceptable to the patient of developing world. FINANCIAL INTEREST: NONE

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