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Comparison of VisThesia&trade and cohesive OVD in phacoemulsification cataract surgery

Poster Details

First Author: E.Cohen ISRAEL

Co Author(s):    A. Michaeli   U. Soiberman   A. Rosenblatt        

Abstract Details


assess the results of phacoemulsification cataract surgery using a cohesive OVD in comparison to VisThesia&trade.


Tel Aviv Sourasky Medical center, Tel Aviv, Israel.


A prospective Randomized Case Control study of 22 patients recruited for elective phacoemulsification cataract surgery, they were randomly assigned in a 1:2 ratio to either receive cohesive OVD with topical anaesthesia (Esracaine&trade gel) and intracameral lidocaine 1% 0.5cc (control group) OR VisThesia&trade alone (visThesia group) during surgery. All patients underwent a complete ophthalmologic examination before the operation and at 4 time points post operatively (1 day, 1 week, 1 and 3 months). Parameters such as endothelial cell count, pachymetry, best corrected visual acuity (BCVA), intraocular pressure, anterior chamber reaction and corneal edema were evaluated. The operation was performed using a single phacoemulsification machine (Infinity&trade, Alcon laboratories, TX, USA) by a single expert cataract surgeon. Following surgery, patients graded the level of discomfort as described by a visual analogue pain scale [1-10].


Fifteen patients were enrolled in the visThesia group and 7 patients to the control group, all parameters were well balanced between the two groups preoperatively with no statistically significant difference. Preoperative BCVA was statistically improved in both groups. Mean BCVA in visThesia group was increased from 0.38 Log MAR ± 0.2 (SD) preoperatively to 0.15 Log MAR ± 0.1 (SD) postoperatively, whereas in the control group BCVA was increased from 0.42 Log MAR ± 0.24 (SD) preoperatively, to 0.15 Log MAR ± 0.1 (SD) after surgery (p= 0.88). The mean decrease in endothelial cell count at three months was 632 cells/mm2 ± 461 (SD) in the visThesia group and 515 cells/mm2 ± 579 (SD) in the control group (p=0.537). There was no statistically significant difference at three month in measured pachymetry in both groups. Intraoperative mean pain score was 1.75 ± 2.3 (SD) in the visThesia group compared to 2.33 ± 1.6 (SD) in the control group (p=0.27). There was no statistically significant difference in intraoperative phaco energy used between groups.


In our small sample study we did not find any significant difference between using VisThesia alone versus topical and intracameral anesthesia with cohesive OVD for uneventful phacoemulsification cataract surgery in parameters of safety, corneal endothelium protection and analgesic effect. FINANCIAL INTEREST: NONE

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