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Intracorneal Bowman layer implantation for progressive advanced keratoconus

Poster Details

First Author: VasilisLiarakos GREECE

Co Author(s):    Korine van Dijk   Jack Parker   Peter Ciechanowski   Gerrit Melles     

Abstract Details


To evaluate the efficacy of Bowman layer (BL) implantation in reducing and stabilizing corneal ectasia in patients with progressive advanced keratoconus (AKC) and contact lens intolerance.


: Netherlands Institute for Innovative Ocular Surgery


Ten eyes of 9 patients with progressive AKC, not eligible for UV-crosslinking, underwent mid-stromal implantation of an isolated Bowman membrane and were followed for a mean of 16 months. Best spectacle corrected visual acuity (BSCVA), maximum and average corneal curvature (Kmax and Kmean) and corneal thickness were recorded at 1, 3, 6, 9 and 12 months postoperatively and every 6 months thereafter.


All surgeries were uneventful and no BL-implantation-related complications were observed. Not only keratoconus was stabilized during follow-up, but there was also a “flattening” effect observed already from the first months. Maximum corneal power decreased on average from 74.5D (±7.1D) to 68.3D (±5.6D) (P<0.001) at last follow-up. BSCVA and corneal thickness did not change significantly (P=0.77 and P=0.11, respectively).


BL implantation may be a safe and effective procedure for preventing further progression and also treating ectasia in AKC, enabling continued contact lens wear and postponing penetrating or deep anterior lamellar keratoplasty. FINANCIAL INTEREST: NONE

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