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Corneal histopathology analysis of first penetrating keratoplasty in congenital aniridia patients

Poster Details

First Author: Maria MontserratBausili Portabella SPAIN

Co Author(s):    Maria Fideliz de la Paz   Francesc Tresserra   Rafael Ignacio Barraquer        

Abstract Details


To evaluate the corneal button of first penetrating keratoplasty of patients diagnosed of Congenital Aniridia.


: Instituto Universitario Barraquer, Centro de Oftalmología Barraquer.


Retrospective analysis of cases diagnosed with congenital Aniridia. We analyze 11 corneal button of 11 eyes with Congenital Aniridia. We just include those patients who underwent penetrating keratoplasty for the first time. The corneal buttons were analyzed for the presence of histological characteristics and vascularization of epithelium, the presence or not of Bowman’s layer, the thickness of stroma and Descemet and endothelium alterations layer.


We found alterations in epithelium and stroma of all the patients. Although this lost of architecture was not seen in Descemet and endothelial population.


Patients with advanced congenital aniridic keratopathy may be good candidate for Deep Aterior Lmellar Krathoplasty (DALK) for the preservation of normal endothelium and descemet membrane. FINANCIAL INTEREST: NONE

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