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First Author: HanyElmekawey EGYPT
Co Author(s): Inas Kamel Ashraf Mounier Ahmad Zaglol Ehab Saied
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Evaluation of the effect of different concentrations of fentanyl added to the local anesthetic mixture on then onset and duration of globe anesthesia, after peribulbar block, with the least side effects.
: Kasr Al Aini hospital, Cairo University, Egypt.
Double blinded randomized controlled clinical trial. 60 patients with cataract grade 1 to ASA grade I, II and III, scheduled for elective cataract surgery under regional anesthesia. They were randomly divided into four groups, in Group 1 (Control Group), patients received Lidocaine 2% and Hyaluronidase 15 IU/ml. In Groups 2, 3 and 4 (Fentanyl Groups), the patients received Lidocaine 2% and Hyaluronidase 15 IU/ml in addition to Fentanyl 1 μg/ml, 2 μg/ml and 3μg/ml respectively. The onset and duration of lid and globe akinesia were assessed. Postoperative Visual Analogue Score was recorded each hour up to 6 hours.
no statistically significant difference between the four groups in the onset and duration of lid and globe akinesia. there was a significant difference between the control group and the fentanyl groups as regard the duration of analgesia that was significantly prolonged in the fentanyl 2 μg/ml and 3 μg/ml groups. In the control group and fentanyl 1μg/ml group, the patients required analgesia after 100-103 minutes from the local anesthetic injection, while in the fentanyl 2μg/ml group, the patients required analgesia after 116±19 minutes and in the fentanyl 3μg/ml group, the patients required analgesia after 144±11 minutes.
Local peribulbar Fentanyl injection in combination with Lidocaine and Hyaluronidase is a safe and effective method in improving postoperative analgesia in patients undergoing cataract surgery. FINANCIAL INTEREST: NONE