Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Bowman’s layer thickness in patients with mitral valve prolapse

Poster Details

First Author: N. Duru TURKEY

Co Author(s):    O. Hashas   E. Goktas   Z. Duru   H. Arifoglu   D. Ulusoy   A. Karatepe Hashas     

Abstract Details


The aim of this study was to compare the Bowman’s layer thickness in patients with mitral valve prolapse (MVP) and healthy individuals.


This cross-sectional comparative case–control study was performed in the Department of Ophthalmology and Cardiovascular Surgery at Kayseri Education and Research Hospital.


A total of 38 eyes from 38 patients with MVP and 34 eyes from 34 age- and gender-matched healthy individuals were included in this cross-sectional study. The thickness of the corneal epithelium, Bowman’s layer, stroma, and Descemet’s membrane – endothelium complex were measured on the central cornea (i.e., corneal apex) and both the inferior and superior halves of the cornea with anterior segment module of spectral domain optical coherence tomography.


No statistically significant differences emerged between the study and control groups in terms of Bowman’s layer thickness in the central cornea and the cornea’s superior half (p=.092 and p=.128, respectively). However, in the inferior half of the cornea, Bowman’s layer thickness among participants in the study group was 11.95±2.34 μm (range 7–16 μm) and in the control group was 13.03±1.62 μm (range 10–16 μm), which made for a statistically significant difference (p=.025).


Our study revealed thinning of Bowman’s layer in the inferior half of the cornea in MVP patients, results that could indicate the onset of keratoconus in patients with MVP.

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