Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Non-penetrating deep sclerectomy vs trabeculectomy for open angle-glaucoma: retrospective study

Poster Details

First Author: M. Noronha PORTUGAL

Co Author(s):    L. Vieira   V. Lemos   B. Carvalho   N. Silva   M. Reina   T. Gomes     

Abstract Details


To compare non-penetrating deep sclerectomy (NPDS) + Esnoper implant with trabeculectomy (TB) + 5-fluorouracil (5-FU) in post-operative reduction of intraocular pressure (IOP), complications and antiglaucoma medication.


Centro Hospitalar Lisboa Central Department of Ophthalmology.


Retrospective study of 40 eyes (40 patients) with open angle glaucoma (primary open angle glaucoma; pseudoexfoliative and pigmentary), that underwent NPDS+Esnoper (20 eyes) and TB+5-FU (20 eyes). Post-operative results (days 1;7;30;90 and 180) of IOP, complications and antiglaucoma medication were quantified and compared. Absolute success was defined as IOP<18 mmHg without antiglaucoma medication at 180 days time. Relative success was defined as IOP <18 mmHg with or without antiglaucoma medication at 180 days time.


In the NPDS+Esnoper group mean IOP and antiglaucoma medication (n) were reduced from pre-surgery values of 26,1+/-5,6 mmHg (n= 3,9+/-0,8) to post-surgery values of 8,3+/-2,8 (n=0); 10,1+/-3,5 (n=0); 13,8+/-3,1 (n=0,1+/-0,3); 14,4+/-3,5 (n=0,2+/-0,5) and 13,6+/-2,3 (n=0,3+/-0,6) at 1;7;30;90 and 180 days. In the TB+5-FU group the reductions were from pre-surgery values of 23,0+/-7,4 mmHg (n=3,6+/-0,6) to post-surgery values of 9,2+/-2,3 (n=0); 10,9+/-3,7 (n=0,1+/-0,2); 14,1+/-5,0 (n=0,3+/-0,5); 16,2+/-5,5 (n=0,5+/-0,6) and 14,3+/-3,6 (n=0,6+/-0,7) at 1;7;30;90 and 180 days. Post-operative complications were 20% in the NPDS+Esnoper group and 30% in the TB+5-FU group. Absolute success rate was 70% for the NPDS+Esnoper group and 55% for the TB+5-FU group (p=0,19). Relative success rate was 95% for the NPDS+Esnoper group and 90% for the TB+5-FU group (p=0,54).


Our results, while obtained retrospectively, show that NPDS+Esnoper seems to be equally effective as TB+5-FU in the post-operative IOP, complications and antiglaucoma medication reduction.

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