Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Refractive effect after FS-LASIK and SMILE, is there any correlation with corneal volume and biomechanical property?

Poster Details

First Author: Y. Wang CHINA

Co Author(s):    P. Wei   J. Zhang                 

Abstract Details


To investigate the potential influence of corneal volume and biomechanical property on refraction changes after small incision lenticule extraction (SMILE) and femtosecond laser–assisted laser in situ keratomileusis (FS-LASIK)


Tianjin Eye Hospital & Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Medical University, Tianjin, China.


A total of 98 eyes that underwent SMILE and FS-LASIK was followed up at 3 months postoperatively. The corneal volume (CV) obtained with Pentacam within 5 mm measurement diameter was defined as central area (CV5), and the diameter from 5 to 10 mm of CV was defined as peripheral area (CV5-10). In addition, corneal hysteresis (CH) and corneal resistance factor (CRF) were obtained with Ocular Response Analyzer (ORA). Statistical significance of CV between above procedures was evaluated by independent-samples t test. Pearson correlation was applied to analyze the correlation between acquired spherical equivalent refraction (△SE), △CRF, △CH, and △CV.


The CV were decreased significantly after both procedures (p<0.05). Significant difference was revealed in the variations of CV from 1 day to 3 months with the value of 0.11±0.16mm3 and 0.20±0.13mm3 in SMILE and FS-LASIK, respectively (p<0.05). The SE at 1 day was significant larger than other follow-ups after FS-LASIK, however, SE got stable after SMILE over times. At 3 months follow-up, the △CV5 showed negative correlations with △SE in SMILE (r=-0.756) and FS-LASIK (r=-0.798), and it was correlated with △CRF (r=0.551) and △CH (r=0.436) in SMILE, however in FS-LASIK it was only correlated with △CRF ( r=0.363).


Corneal volume was changed over time after both SMILE and FS-LASIK. Corneal biomechanics were affected by the variations of CV after surgery, which maybe have correlation with refractive changes, or even refractive regression.

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