Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Corneal stroma demarcation line depth after corneal collagen cross-linking in keratoconus and bullous keratopathy

Poster Details

First Author: M. Shinzawa JAPAN

Co Author(s):    N. Kato   K. Kasai   K. Konomi   K. Higa   J. Shimazaki        

Abstract Details


The aim of our study was to compare the corneal stroma demarcation line depth (DLD) after corneal collagen crosslinking (CXL) in patients with progressive keratoconus and advanced bullous keratopathy.


Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan


A retrospective analysis of 20 eyes with progressive keratoconus and 10 eyes with advanced bullous keratopathy were treated with CXL. We performed CXL using the accelerated CXL protocol (5 minutes of continuous irradiation time at 18 mW/cm2 UV intensity) using the KXL® System (Avedro Inc., USA) and measured the DLD of all eyes using anterior segment optical coherence tomography (AS-OCT) at 1 month.


In the keratoconus group, the mean DLD was 295.1 µm ± 54.72 (SD). In the bullous keratopathy group, the mean DLD was 365.2 µm ± 39.61 (SD). The DLD was statistically significantly deeper in the bullous keratopathy group than in the keratoconus group (p = 0.001, t test for unpaired data).


Despite using the same CXL protocol, the difference in the DLD was statistically significant between the keratoconus and bullous keratopathy groups. Further study is needed to determine why.

Financial Disclosure:


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