Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Nationwide reduction in the number of corneal transplantations for keratoconus following the implementation of cross-linking

Poster Details

First Author: D. Godefrooij NETHERLANDS

Co Author(s):    R. Gans   S. Imhof   R. Wisse              

Abstract Details


Keratoconus is characterised by corneal ectasia and irregular astigmatism, which can lead to diminished vision and corneal scarring. Approximately 10-20% of patients with keratoconus eventually require a corneal transplant. Corneal cross-linking (CXL) is a relatively new treatment that may help prevent the need for corneal transplantation. Here, we investigated whether the introduction of CXL has reduced the number of corneal transplants performed annually within the Netherlands.


Registry study Utrecht Cornea Research Group, Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands.


Data regarding the transplantation procedures performed in patients under the age of 50 years were extracted from the Dutch National Organ Transplant Registry. The number of corneal transplants performed prior to (i.e., in 2005 through 2007) and following the introduction of CXL (i.e., in 2012 through 2014) were compared.


Approximately 25% fewer corneal transplants were performed in the 3-year period following the introduction of CXL compared to the 3-year period prior to the introduction of CXL (201 versus 269 transplants, respectively; P=0.005). Age, gender, and visual acuity were similar between the patient groups in the two time periods.


Significantly fewer corneal transplants were performed for treating keratoconus following the nationwide introduction of CXL within the Netherlands. This reduction suggests that corneal crosslinking can significantly reduce the need for corneal transplantation.

Financial Disclosure:


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