Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Clinical outcomes after implanting donor tissue torn during graft preparation in Descemet's membrane endothelial keratoplasty: a prospective study

Poster Details

First Author: C. Panthier FRANCE

Co Author(s):    R. Courtin   D. Gatinel   A. Saad              

Abstract Details


To evaluate the incidence and clinical impact of implanting donor tissue torn during manual preparation for the Descemet’s membrane endothelial keratoplasty (DMEK) procedure.


Single center prospective study Rothschild Foundation, France


175 DMEK procedures from a single surgeon were included. with11 cases of torn donor tissue noted within the group. We compared data from control cases with intact grafts. Best-corrected visual acuity (BCVA), specular microscopy of the donor tissue with endothelial cell density (ECD) and central corneal thickness of the recipient were recorded pre-operatively and again 1, 3, and 6 months after surgery.


In the torn graft group mean central corneal thickness (CCT) decreased from 667.1 ±82.7µm preoperatively to 569.3±14.2µm at 1 month, 533.6µm ±59.3µm at 3 months, and 528µm ±55.9µm at 6 months. CCT was higher in the torn graft group at one month after surgery compared to the controls (P=0.04) but not afterwards. BCVA in the torn graft showed no significant differences when compared to controls. The ECD loss at six months was 36.6% in the torn graft group and 31.8% in the control group respectively with no significant difference (P>0.05) found. The ECD loss between the preoperative and 1 month postoperative values was significantly higher in the torn graft group (P= 0.04).


The presence of a tear during the graft preparation does not impact the final long-term clinical outcome or post-operative visual acuity but the recovery time does seem to be slower

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