Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Combined cataract and endothelial keratoplasty in Fuchs endothelial dystrophy: DSEK vs DMEK

Poster Details

First Author: N. Kopsachilis UNITED KINGDOM

Co Author(s):    E. Hollick                    

Abstract Details


To report 6-month and 1-year endothelial cell loss (ECL), intra- and postoperative complications and best corrected visual acuity (BCVA) in a large series of patients with Fuchs endothelial dystrophy (FED) undergoing either a combined phacoemulsification and Descemet’s stripping endothelial keratoplasty (DSEK) or combined Descemet’s membrane endothelial keratoplasty (DMEK) and phacoemulsification in a UK centre.


King's College Hospital, London


Consecutive patients with FED undergoing DSEK or DMEK with cataract surgery were included in this retrospective study. Patients with glaucoma or complex anterior segment pathology were excluded. Main outcomes included intra- and postoperative complication, percentage ECL and BCVA.


DSEK combined with cataract surgery was performed in 79 eyes (80 patients). The mean percentage ECL at 6 and 12 months was 40.4±15.4 and 41.5±15.3. 31 eyes (29 patients) underwent the combined DMEK and phacoemulsification procedure with a mean percentage ECL at 6 and 12 months of 33.0±12.5 and 33.7±15.5 respectively. Intraoperative complications occurred in three patients undergoing DSEK and none undergoing DMEK. Postoperative complication rates were not statistically significant between the 2 groups and BCVA of 6/9 or better was similar in both groups.


Mean ECL was less but not statistically significant in the DMEK group at 6 and 12 months (p=0.24) and postoperative vision was similar in both groups. The complication rate was comparable between the two groups.

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