Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Corneal microstructural changing after cataract surgery using a topical solution with hyaluronic acid and ginko biloba extract

Poster Details

First Author: A. Canovetti ITALY

Co Author(s):    A. Malandrini   I. Lenzetti   F. Rossi   L. Menabuoni           

Abstract Details


To study the corneal microstructural changes after uneventful cataract surgery using postoperatively an ophthalmic sterile solution containing synthetic hyaluronic acid and ginko biloba extract (Trium®).


Ophtalmology Department, Nuovo Ospedale di Prato Santo Stefano, Prato, Italy


22 healthy patients were investigated after uneventful ultrasound cataract phacoemulsification with intraocular lens insertion using postoperatively Trium® eyedrops three time a day for 6 months. A complete ocular evaluation and confocal microscopy were performed at 1, 3 and 6 months after surgery. Sub-basal nerve plexus density was quantitatively analyzed: the density was calculated in the central cornea as number of fibers per field.The other eye was taken to make the comparison.


At 1 month postoperatively, surgery reduced the sub-basal nerve fibers by 25-35% in comparison with the other eye. Important changes were shown in the central cornea up to 3 months after surgery: a reduction in nerve fiber number (month 1: 1.4 ± 0.5, p < 0.0001; month 3: 2.4 ± 1.1, p < 0.005) was easily detected. The confocal parameters progressively recovered thereafter (month 6: +2.7 ± 1.9). Better stability of ocular surface considering Break-up Time was found throughout the study. No relevant side effects were recorded by using the topical Ginko biloba extract.


Sub-basal nerve density was reduced after cataract surgery. Ginko biloba extract could help to restore it and to maintain the surface integrity avoiding patient discomfort.

Financial Disclosure:


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