Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Presbyopic refractive error aggravates dry eye disease

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Session Details

Session Title: Presented Poster Session: Presbyopia

Session Date/Time: Tuesday 13/09/2016 | 09:30-11:00

Paper Time: 10:00

Venue: Poster Village: Pod 2

First Author: : E.Mai TAIWAN

Co Author(s): :    D. Chang              

Abstract Details


To investigate if presbyopic induce accommodative spasm can be a factor in causing or aggravating Dry Eye Disease.


Teaching hospital clinical observational study combines with National Health Insurance database (population data base), 14 years of retrograde data statistic analysis


26193 Presbyopic cases and 122959 age-matched control subjects were recruited using the National Health Insurance database. Kaplen-Meier Survival analysis method where use to calculate the Hazard rates of these patients becoming Dry eye. Using Stratified Cox Proportional Hazard model, confounding factors such as DM, Allergic eye, post surgery status where adjusted and the Hazard rate ratio where obtained. 25 patients from Dry eye clinic were recruited into a observational study, dry eye disease where established by traditional methods. Hyperopic/Presbyopic corrective glasses where prescript and patients were follow up with OSDI(ocular surface disease index) and other dry eye indexes.


The Kaplen-Meier survival curve shows a significant difference between those cases who had presbyopia and those that do not have presbyopia diagnosis. After adjusting for confounding factors with Cox model, the Hazard Ratio was calculated to be 2.61, showing a significant increase of risk for those that have presbyopia to acquire Dry eye disease. In the clinical oberservational study, full hyperopic corrections and near corrections of glasses were given to the 25 cases, the OSDI shows improvements of symptom signs as soon as 1 weeks time.


We have statistically proved that the risk of having dry eye disease is much higher if the patient had presbyopic refractive errors. Clinically follow up of dry eye patients with aggressive treatment of this refractive error such as use of full corrective glasses show an improvement of OSDI. We therefore proposed that Presbyopic refractive error can aggravate dry eye disease.

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