Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Assessment of corneal epithelial defect by ultrahigh-resolution optical coherence tomography

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Session Details

Session Title: Presented Poster Session: Anterior Segment Imaging

Session Date/Time: Monday 12/09/2016 | 09:30-11:00

Paper Time: 09:30

Venue: Poster Village: Pod 4

First Author: : G.Fuchsjäger-Mayrl AUSTRIA

Co Author(s): :    R. Werkmeister   K. Fondi   G. Garhofer   G. Schmidinger   L. Schmetterer   D. Schmidl

Abstract Details


To investigate the correlation between corneal epithelial defect size as assessed by ultrahigh resolution optical coherence tomography (OCT) and from slit lamp photographs.


Forty patients with keratoconus after epi-off corneal collagen cross linking were included. The study was conducted at the Department of Ophthalmology in cooperation with the Department of Clinical Pharmacology and the Center for Medical Physics and Biomedical Engineering of the Medical University of Vienna.


Epithelial defect size was assessed with a costum-built ultrahigh-resolution OCT system with a theoretical axial resolution of 1.2µm in corneal tissue. In addition, slit lamp photography with fluorescein staining was performed. From these photographs, the ratio of corneal wound area to iris area was calculated. Patients were followed up every other day until wound healing was achieved.


Linear correlation analysis revealed excellent agreement between the defect size as measured with OCT and the defect size as measured based on slit lamp photography (r=0.89, p<0.001).


Monitoring of corneal wound healing using ultrahigh-resolution OCT seems to be an attractive alternative to fluorescein staining, since it provides an objective, non-invasive and three-dimensional evaluation of the corneal defect.

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