Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Re-bubbling techniques for graft detachment after Descemet's membrane endothelial keratoplasty

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Session Details

Session Title: Moderated Poster Session 03: Spotlight on Corneal Surgery

Session Date/Time: Monday 12/09/2016 | 14:00-15:00

Paper Time: 14:50

Venue: Poster Village: Pod 1

First Author: : E.Fernández López THE NETHERLANDS

Co Author(s): :    L. Baydoun   N. Gerber-Hollbach   I. Dapena   V. Liarakos   L. Ham   G. Melles

Abstract Details


To describe re-bubbling techniques in eyes with a visually significant graft detachment after Descemet's membrane endothelial keratoplasty (DMEK).


Netherlands Institute for Innovative Ocular Surgery / Tertiary referral center.


Retrospective observational analysis at a tertiary referral center. A total of 41 eyes (39 patients) received re-bubbling: 39 eyes (37 patients) had a single and two had two re-bubbling procedures. Anterior segment optical coherence tomography and surgical videos were used to determine the best incisional approach for air injection, intraoperative maneuvers, and the success rate (graft re-attachment) at one week postoperatively.


Re-bubbling was performed on average 26 (±21) days (range: 7-92 days) after DMEK. Graft-edge visibility and graft detachment type were important parameters for the area of air injection: either where the graft was attached ('attached area approach') (n=25) or detached ('detached area approach') (n=16). Excluding upside-down grafts (n=3), resulted in a total re-bubbling success rate of 87% (33/38 eyes); ‘attached area approach’ 92% (22/24 eyes) and the ‘detached area approach’ 79%, (11/14). Fourteen eyes were re-bubbled after one month postoperatively; 11 were successful, but in eight eyes the graft appeared too stiff and/or immobile to allow complete unfolding.


Re-bubbling is a feasible procedure to manage graft detachment after DMEK if the graft is correctly oriented. Proper preoperative planning may aid in minimizing intraoperative complications and may increase the success rate. Late interventions (> one month postoperatively) may still produce graft attachment, but increased graft stiffness and/or fibrosis may complicate complete graft unfolding.

Financial Disclosure:

One or more of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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