Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Two-year refractive outcomes after Descemet's membrane endothelial keratoplasty

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Session Details

Session Title: Moderated Poster Session 03: Spotlight on Corneal Surgery

Session Date/Time: Monday 12/09/2016 | 14:00-15:00

Paper Time: 14:30

Venue: Poster Village: Pod 1

First Author: : K.Van Dijk THE NETHERLANDS

Co Author(s): :    M. Rodriguez-Calvo-de-Mora   I. Dapena   L. Baydoun   S. Oellerich   G. Melles  

Abstract Details


To monitor the refractive change and stability after Descemet's membrane endothelial keratoplasty (DMEK) and to determine which parameters may influence the refractive change and the time point of stabilization.


Netherlands Institute for Innovative Ocular Surgery / Tertiary referral center


In this retrospective evaluation of prospectively collected data, biomicroscopy and measurements on visual acuity, subjective refraction and Scheimpflug based corneal tomography were evaluated before, and up to 2 years after surgery for 67 eyes out of a series of 168 consecutive pseudophakic DMEK eyes operated on for Fuchs endothelial dystrophy (FED). Main outcome measures were visual acuity and changes in spherical equivalent (SE), mean anterior and posterior simulated keratometry (Km), and central pachymetry.


At 3 months postoperative, 42% of eyes showed a hyperopic and 31% a myopic shift, 27% showed no change. The mean change in SE was +0.33 diopters (95% CI=[0.11,0.54], P=.028),. Mean anterior Km initially flattened (P<.001), posterior Km steepened (P<.0001), and mean central pachymetry deceased (P<.0001). Whereas mean SE, posterior Km and pachymetry stabilized at 3 months postoperatively (P>.252), mean anterior Km steepened between 1-2 years postoperative (P<.001). Pre- to 3 months postoperative changes in SE and anterior and posterior Km related positively to preoperative FED stage (P<.045), and larger changes in anterior Km related to partial graft detachment (P=.007).


DMEK may give a minimal refractive change from preoperative to 3 months after surgery, after which most refractive parameters may remain stable up to 2 years after DMEK. Larger refractive shifts may be related to more advanced FED or postoperative partial graft detachment.

Financial Disclosure:

One or more of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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