Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


escrs app advert yo advert

Outcomes of CO2 laser-assisted sclerectomy surgery (CLASS) for open-angle glaucoma treatment

Search Title by author or title

Session Details

Session Title: Presented Poster Session: Glaucoma

Session Date/Time: Sunday 11/09/2016 | 15:00-16:30

Paper Time: 16:00

Venue: Poster Village: Pod 3

First Author: : C.Cutolo ITALY

Co Author(s): :    A. Bagnis   R. Scotto   C. Traverso        

Abstract Details


The aim of this study was to evaluate the clinical safety and efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) in patients with primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (XFG).


Eye Clinic, DINOGMI, University of Genoa, Italy.


The authors retrospectively reviewed the acquired database of all patients treated with the CLASS procedure at our institution. A single surgeon performed all CLASS procedures using IOPtiMate system (IOPtima Ltd., Tel Aviv, Israel). After the dissection of a partial thickness scleral flap, topical Mitomycin C 0.2 mg/ml was applied for 3 minutes. The CO2 laser with a beam-manipulating system was used to ablate the scleral tissue in favour of reservoir creation for the percolated aqueous absorption, and to expose the Schlemm's canal area until sufficient percolation was obtained. Intraocular pressure (IOP), medications and complications were evaluated.


Twenty-four eyes (21 POAG and 3 XFG) underwent the CLASS procedure. With a follow-up time (FU) of 15.7±6 months (mean ± SD), the IOP changed from 25.3±6.9 mmHg preoperatively to 11.2±3.8 mmHg (p<0.001) at last FU visit. The number of IOP-lowering drugs decreased from 3.5±0.9 before surgery to 1.0±1.1 (p<0.001). Seven eyes developed iris apposition at the trabeculo-descemetic window; this was successfully managed at the slit-lamp (4) or with 2% pilocarpine and Nd:YAG laser synechiolysis (3). In one case, the procedure was converted to trabeculectomy due to intraoperative perforation. There was one case of hypotony maculopathy successfully treated with placement of additional transconjunctival scleral flap sutures. Post-operative bleb needling was performed in 8 eyes.


Our data suggest that CLASS procedure is safe, with good clinical outcomes. Irido-trabecular contacts warrant further evaluation and possibly reflect the surgeon's learning curve.

Financial Disclosure:

One or more of the authors travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

Back to previous