Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Simultaneous corneal wavefront-guided photorefractive keratectomy and corneal CXL after ICRS implantation for keratoconus

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Session Details

Session Title: Presented Poster Session: Cross-linking

Session Date/Time: Sunday 11/09/2016 | 09:30-11:00

Paper Time: 10:20

Venue: Poster Village: Pod 3

First Author: : D.Kang SOUTH KOREA

Co Author(s): :    B. Ha   J. Choi   H. Lee   Y. Ji   T. Kim  

Abstract Details


To study the results of simultaneous corneal wavefront guided(CWFG) trans –epithelial photorefractive keratectomy (t-PRK) and corneal collagen crosslinking (CXL) in keratoconus after previous intrastromal corneal ring segment (ICRS) implantation.


Eyereum Eye Clinic, Seoul,Korea. Institute of Vision Science, Department of Ophthalmology Severance Hospital, Yonsei University School of Medicine.


This study comprised 72 eyes of 61 patients with moderate keratoconus who had previous Keraring ICRS implantation with the Intralase laser at least 1 month before t-PRK-CXL. CWFG t-PRK and CXL were performed simultaneously. Refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, keratometry (K) values, endothelial cell count (ECC), pachymetry, corneal wavefront Zernike indices, Corvis ST indices were assessed upto 1 year postoperatively.


12 months after t-PRK-CXL, mean UDVA improved significantly from 0.34 ± 0.13 (SD) to 0.61 ± 0.11 (P<.01). Mean CDVA improved from 0.75 ± 0.25 to 0.86 ± 0.07 (P=.01). No patient lost lines of CDVA. The mean cylinder decreased from -2.8 ± 1.96 to -1.45 ± 1.40 diopters (D) (P<.001). The mean apex K decreased from 52.44 ± 7.82 D to 47.24 ± 4.92 D (P<.005). Corneal coma decreased from 2.48 ± 1.9 Microns to 2.03 ± 1.13 after ICRS implantation which subsequently decreased further to 0.542 ± 0.26 after CWFG T-PRK and CXL. Inverse Concave radius increased from 0.165 ± 0.03 to 0.201±0.03 and 0.205±0.05 (p<0.1).


Simultaneous corneal wavefront-guided t-PRK and CXL for keratoconus after ICRS implantation was safe and effective. It significantly improved the UDVA, CDVA, apex K value, and corneal coma of patients with moderate keratoconus.

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