Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Opaque bubble layer in small incision lenticule extraction

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Session Details

Session Title: Presented Poster Session: Laser Refractive Surgery (Lasers/LASIK/Epi-LASIK)

Session Date/Time: Sunday 11/09/2016 | 09:30-11:00

Paper Time: 10:20

Venue: Poster Village: Pod 2

First Author: : G.Son SOUTH KOREA

Co Author(s): :    T. Lim   J. Lee   C. Jang        

Abstract Details


To report the development of opaque bubble layer (OBL) in the small incision lenticule extraction (SMILE) and to analyze its risk factors and associations to the clinical outcome.


A retrospective analysis of medical records and video record of operation.


208 consecutive eyes of 106 patients underwent SMILE and were followed up at least 3 months. The comprehensive analyses of the video records were performed and the amount of pixels of early OBL area after the lenticule cut was calculated with computer software. Each patient was divided into 2 groups, group A (OBL less than 5% of cornea) and group B (OBL more than 5% of cornea). The preoperative parameters and clinical outcomes at the 3rd postoperative month were compared and the extents of early OBL was analyzed its associations to various parameters by linear regression analyses.


In 96 eyes (46.15%, group B) OBL developed more than 5% of total corneal area. Thicker cornea (570.25 ± 29.46 um vs. 555.84 ± 27.12 um, p=0.002) and thinner ablation depth (87.50 ± 23.82 um vs. 101.69 ± 23.22 um, p<0.001) was presented in Group B (vs. group A) More surgical time (p<0.001) elapsed in group B (421.67 ± 132.08 sec) than in group A (290.56 ± 46.71 sec). The efficacy (p=0.062) and the safety (p=0.068) were equivalent, and the predictability of group B was 93.75%, 100% and 100% within ±0.5D, ±1.0D, ±2.0D respectively and 100% in ± 0.5D in group A. Corneal thickness (p=0.001), ablation depth (p<0.001) was analyzed to affect the amount of OBL. (R2 = 0.219)


The more OBL tends to develop in eyes with the thicker cornea or with the less ablation thickness. The presence OBL noes not yield negative effects to the overall clinical outcomes except slightly lower predictability value and longer operation time.

Financial Disclosure:


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