Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Rho-associated kinase (ROCK) inhibitor role in the management of persistent corneal graft edema

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Session Details

Session Title: Presented Poster Session: Medical Cornea

Session Date/Time: Saturday 10/09/2016 | 09:30-11:00

Paper Time: 10:40

Venue: Poster Village: Pod 3

First Author: : H.Hasani IRAN

Co Author(s): :    A. Baradaran-Rafii   R. Shamsoddini Motlagh           

Abstract Details


To report cases of corneal persistent graft edema that was successfully treated by Rho-associated kinase (ROCK) inhibitors.


Ophthalmology Department, Alborz University of Medical Sciences


Three eyes unresponsive to medical Treatment (BCVA ≤4/100) underwent sub-conjunctival Fasudil injection (0.5 mg/1 ml) 2 times with two weeks interval time.


Corneal clarity recovered and vision improved 4-6 weeks after the second injection. At three months, vision improved to 20/160. Average central corneal thickness was 579+/-10 μm, significantly lower than its pretreatment value (744+/-9 μm).The average corneal endothelial density in the central cornea increased from 894 ± 64 to 1549.3 ± 98 cells/mm³.


These cases highlight the possibility of the use of subconjunctival ROCK inhibitors as an alternative to regraft surgery for certain forms of persistent corneal graft edema.

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