Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Effectiveness of CacicolĀ® in the treatment of corneal defects and restoring ocular surface

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Session Details

Session Title: Presented Poster Session: Medical Cornea

Session Date/Time: Saturday 10/09/2016 | 09:30-11:00

Paper Time: 10:10

Venue: Poster Village: Pod 3

First Author: : I.Garcia Del Moral SPAIN

Co Author(s): :    J. Martinez Jerez   A. Solans Perez De Larraya   M. Gonzalez Gallardo        

Abstract Details


The aim of our pilot study was to investigate if a solution of a regenerating agent, an heparan sulfate analogous, was effective in the treatment of corneal defects involving epithelium and stroma and thus in restoring the ocular surface. This regenerating agent is a matrix structure that permits the fixation and the protection of the components involved in the tissue regeneration process.


Complejo Hospitalario Universitario de Granada (CHURG). Spain.


We selected 8 patients with corneal ulcers secondary to Neurotrophic Keratopathy (2 of the patients) and corneal epithelial persistent defects (6 of them) who were not responding to usual treatment. They were given CacicolĀ® twice a week for 1-2 months and in further visits biomicroscopic and OCT analysis was performed in order to demonstrate corneal healing.


At the end of the treatment with this regenerating agent, all the patients presented total healing of the corneal defects, observed with biomicroscopic exam and OCT. There were no local or systemic adverse effects due to this treatment.


The results obtained in our case series demonstrate the effectiveness of CacicolĀ® as a therapy for corneal epithelial persistent defects and Neurotrophic Keratopathy.

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