Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance

10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits


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Clinical outcomes of small incision lenticule extraction (SMILE) and femtosecond laser-assisted wavefront-guided laser in situ keratomileusis (WFG-LASIK): a review

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Session Details

Session Title: Presented Poster Session: Keratorefractive Surgery Outcomes: Myopia

Session Date/Time: Saturday 10/09/2016 | 15:00-16:30

Paper Time: 16:00

Venue: Poster Village: Pod 2

First Author: : D.Piñero Llorens SPAIN

Co Author(s): :    M. Teus              

Abstract Details


To review the scientific literature published to date on the clinical outcomes of SMILE and WFG FS-LASIK techniques for the correction of myopia or myopic astigmatism


University of Alicante (Alicante, Spain), University of Alcala (Madrid, Spain)


A bibliographic search was performed in PubMed and Google Scholar to find articles from January 2012 to September 2015 reporting the outcomes after SMILE and WFG FS-LASIK for the correction of myopia or myopic astigmatism. A total of 74 relevant articles was found, after excluding letters to editor and articles reporting the outcomes of ReLEx femtosecond lenticule extraction (FLEx) (previous technique to SMILE). The results were analysed following this scheme: visual and refractive outcomes, ocular and corneal aberrometric outcomes, contrast sensitivity results, impact on corneal sensation and dry eye, corneal backscattering changes, corneal biomechanical changes, and complications.


Both SMILE and WFG FS-LASIK provide good visual outcomes and an efficacious correction of the refractive error, with postoperative uncorrected distance visual acuity ranging from 0.01 to -0.20 logMAR. The safety of both procedures was good, with no clear differences in terms of losses of lines of corrected distance visual acuity (CDVA) among techniques. Spherical equivalent was within ±0.50 D in 67.60% to 100% and in 80% to 100% of eyes after SMILE and WFG FS-LASIK, respectively. Concerning aberrations, a trend to more postoperative coma was reported after SMILE, with no consistent differences for other aberrations. Corneal sensitivity was reduced less after SMILE due to less severe decrease in subbasal nerve density. Significant corneal biomechanical changes occur after both techniques.


Both SMILE and WFG FS-LASIK are effective and safe for the correction of myopia or myopic astigmatism. Except for the difference in the impact on subbasal nerve density, more consistent scientific evidence is still required to confirm the superiority of one technique over the other.

Financial Disclosure:


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