Copenhagen 2016 Registration Programme Exhibitor Information Virtual Exhibition Satellite Meetings Glaucoma Day 2016 Hotel Star Alliance
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10 - 14 Sept. 2016, Bella Center, Copenhagen, Denmark

This Meeting has been awarded 27 CME credits

 

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Ocular methicillin resistant staphylocCocus aureus infection in a Chinese population: an overview on epidemiology, clinical features, antibiotic susceptibility and proposed treatment protocol – a 10-year hospital-based study

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Session Details

Session Title: Inflammation and Pathology

Session Date/Time: Sunday 11/09/2016 | 14:30-16:00

Paper Time: 14:48

Venue: Hall C2

First Author: : E.Wong CHINA

Co Author(s): :    C. Chow   W. Luk   K. Fung   K. Li           

Abstract Details

Purpose:

To characterize local epidemiological data on Methicillin Resistant Staphylococcus Aureus (MRSA) ocular infections over a 10-year period in a Chinese population in Hong Kong and compare and contrast characteristics between MRSA and Community Associated MRSA (CA-MRSA) ocular infections. Based on the results of the study, to propose a treatment protocol.

Setting:

United Christian Hospital and Tseung Kwan O Hospital of Hong Kong

Methods:

Retrospective, observational case series. Clinical records of patients with ocular samples that tested positive for MRSA over a 10-year period from 2005 to 2015 were reviewed. Data of patients with MRSA ocular infections were analysed. A literature review was performed to compare epidemiological data on MRSA ocular infections across different studies.

Results:

A total of 75 patients and 90 eyes with ocular MRSA infection was found during the 10-year period from July 2005 to July 2015. The average annual rate of ocular MRSA infection among all ocular S.aureus infections was 12.9%; 10 patients had CA-MRSA (13.3%). Preseptal cellulitis was the most common clinical manifestation in the CA-MRSA group vs blepharoconjunctivitis in the MRSA group. Vision threatening conditions occurred only in the MRSA group. Besides vancomycin, both groups remained highly sensitive to chloramphenicol, fusidic acid, minocycline and gentamicin. CA-MRSA was significantly more sensitive to levofloxacin and clindamycin. The MRSA group required a significantly longer duration of treatment and more combination of eyedrops in order to eradicate infection.

Conclusions:

There is a rising trend of MRSA and CA-MRSA infections in both the hospital and community setting. Ophthalmologists should take an active role in curbing the tide against multi- drug resistant microorganisms and actively identify, adequately treat and prevent the spread of infection by such microorganisms. Vancomycin use should be limited to severe refractory or vision threatening conditions in order to prevent the development of resistant microorganisms.

Financial Disclosure:

NONE

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