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Corneal confocal microscopy in diabetic patients

Poster Details

First Author: S.Fazio ITALY

Co Author(s): P. Mellace   F. Martino   E. Polito              

Abstract Details


To evaluate the role of corneal confocal microscopy (CCM) in the diagnosis of morphologic damage of the corneal sub-basal nerve plexus in diabetic patients and to correlate corneal confocal microscopy findings with severity diabetic disease.


Ophthalmology Unit, Department of Medical, Surgical and Neurosciences - Siena University, Italy


In this prospective study were measured the corneal nerve fiber density (CNFD) in twenty-eight patients with diabetes (DM group) and twenty-four healthycontrol subjects using a Heidelberg Retina Tomograph with Rostock Cornea Module.


The total CNFD were significantly shorter in the DM group than in the control group and tended to decrease with progression of diabetic retinopathy, nephropathy.


CCM represents a new tool in the diagnosis, clinical evaluation, and follow-up of peripheral diabetic neuropathy. Diabetes damages corneal nerves, particularly the corneal sub-basal nerve plexus. This damage may be documentedusing CCM.

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